DPCstruct | MC21470

Metacluster Properties and Pfam Annotations

Number of structural domains155
Mean domain length (aa)144 ± 23 aa
Standard deviation of domain lengths22.56
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.83
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)17.71
Pfam Score98.15
Assigned Pfam label(s) CL0345- CL0198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A363TAE9 8-136 PFKLKDFHSVDPKHIARLEAVGVKTADQILKAGRTSPGRSDLAARAGIPPEAILELVKLSDLSRLPGVKGIRARLYYAAGVDTVEKL…
A0A662M1A8 4-119 MKITEIKGIGPKYANKLKKAGIKTVYDLREMNIKSVSKAAGIGEQTLAKWKEEAMKMRLLTDIKGIGDAFRKKLEKHGIRTIEELSK…
A0A182ALN0 1-100 None
A0A353YZC8 90-223 None
A0A7C2XYB2 20-213 None
A0A842TFR3 3-138 None
A0A842TFW1 6-115 None
A0A6N6Q0B3 373-541 None
A0A7Z9Y2B7 259-467 None
A0A378N7N8 52-206 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.