DPCstruct | MC214

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)249 ± 34 aa
Standard deviation of domain lengths33.78
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score88.37
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.69
Pfam Score100.00
Assigned Pfam label(s) PF10592

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D5BTE2 60-336 LSEAKRKQFLTEYPRQQMFTKTDLAKYEVSFAGKPHIVSQGAQKNFISFASEIAKTWEKDDAYFSEQWFKDAVAKAIIFKEVDKMVM…
A0A849L6V2 14-248 AAQKNFAAFAREIGEAWSKSDVGYDELWYRRLIAKAIIFRKLEAEVPKQPWYEGGYRANIVTYAMAKVFHDANSDNQVLDLDAIWRR…
A0A1W2CSY4 7-206 None
A0A180F506 4-235 None
A0A550DXZ5 67-302 None
A0A845I1E2 603-882 None
A0A8A3S5C5 379-667 None
A0A1V3P9M9 1-197 None
A0A6L4LJ73 368-615 None
A3JQZ2 1-273 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.