DPCstruct | MC21382

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)136 ± 20 aa
Standard deviation of domain lengths19.82
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score89.28
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)41.87
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287V925 26-171 EGNDSSTRDEDIALVIPPVFDGCTKVLDADDQKAARDLYWEAVCSDDEATDRSKVEELLRQSVTKNPFVGEPRLVLAQMCLNAEMYE…
A0A7S1FWQ6 283-396 VPLVFRRCTEVLSHADETAARDRYWDVTLHEKKMTADRQIELLRESVSLNPHVGEPHLLLSQLYFRQGDYLAAATEARESLEKLYVL…
A0A645FPZ8 3-105 None
A0A7L5A5B6 151-323 None
A0A261XTR4 502-625 None
A0A2E3ER64 52-184 None
A0A6A6MIX3 209-340 None
A0A7N2KK48 192-354 None
A0A5C7S2A1 168-280 None
A0A7S1Z8Y0 132-248 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.