DPCstruct | MC21364

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)138 ± 10 aa
Standard deviation of domain lengths9.61
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score84.03
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)57.51
Pfam Score87.27
Assigned Pfam label(s) PF16712- PF16711

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G7KL71 40-179 DQIEEGAKLREVPSLEGHVLLKKQRDALEYLKGRFTGRNKEDVANSISMVEALAVKLTQKNEGELIQEKFKVKKLLNFLKQASEDAK…
A0A446VM25 55-191 MKFEKGLSTATLLSNEVKCKQVALLERDILPKNLKSVLESLRGQVAGKYKDEIEESVSMVDILAVQLSKTENELLQQKTEVTRIATS…
A0A6D2HUV4 508-656 None
A0A3B6KG25 18-146 None
A0A484N039 69-215 None
A0A2I0X1C1 159-300 None
A0A1D6G9T5 80-214 None
A0A396HGZ1 5-131 None
A0A6J0NCB0 1-129 None
A0A5N5HU03 81-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.