DPCstruct | MC21349

Metacluster Properties and Pfam Annotations

Number of structural domains431
Mean domain length (aa)267 ± 64 aa
Standard deviation of domain lengths63.82
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score80.19
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.32
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)15.85
Pfam Score68.93
Assigned Pfam label(s) CL0123- PF00239- CL0167- PF14287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X7MFY8 4-218 QVHLFSGGIIRCAHCGFAVTGERIRRNLLDGSVREHVYYRCANNSKPDEHPPMRWREGDLAEMFVEEFKTFVMPTEIAQWFRASIQT…
A0A135WFP8 51-314 NFHPSTISSLLERRTYIGETNFKSSKFGEEITLKDTHEGIVTLEEYLQVREILANKQKFNTRTHAVTSPLDKLIYCKKCRRLMQVNL…
A0A1G5FYZ9 20-256 None
A0A1C2Y043 123-470 None
A0A347Q4I3 173-491 None
A0A6G4V236 29-248 None
A0A1Q6LGQ3 36-294 None
A0A7W8XL15 4-250 None
A0A0P6XLY3 165-381 None
A0A6J4N1V8 279-694 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.