DPCstruct | MC21347

Metacluster Properties and Pfam Annotations

Number of structural domains644
Mean domain length (aa)95 ± 21 aa
Standard deviation of domain lengths21.38
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score75.44
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)34.72
Pfam Score99.57
Assigned Pfam label(s) CL0081- CL0029- CL0263- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U3LM11 118-183 RKKNENTRSRYKGVWWEKDSQKWRAAIKMNNKRYHIGNYYHEREAALAYDKKARELFGEFARLNFP
A0A7S0ILC8 6-94 SQGFARGSSGFRGVTQHPNGRWEARIGMPNSKHIYLGLYNEESAAARAYDMALVRLRGPGAATNYTLANYKDELKAFENDKPGGAQL…
A0A7S3JNR4 32-148 None
A0A7S3N4K7 28-128 None
A0A7S3N8K2 4-101 None
A0A5J5UPQ7 30-100 None
F6GVQ7 12-122 None
A0A165Y472 11-122 None
K8ENL8 68-185 None
A0A6P5HF65 27-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.