DPCstruct | MC21328

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)275 ± 37 aa
Standard deviation of domain lengths36.63
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.81
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)34.28
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A085VZK4 1-252 MPAADIQSAATSIFTQLEAAEFSTQRYALLFKPGTYNVTFNVGFYTHVAGLGQHPDNVTINGGVNVNADWDNGNATRNFWRAIENLS…
A0A378MF73 2-244 VIFSPQDDQARINKKMDAIYKKQKDAQFGPDRFGVYFLPGDYTKGQPNHVYNIGYYTSINGLGAVPTQTKLANVASPAALPDNNGTC…
A0A812RA58 2-279 None
A0A7W8J1S2 1-208 None
A0A4R8WS51 52-377 None
A0A7S1ZMJ0 2-230 None
A0A175XZS0 270-549 None
Q1ZN36 262-563 None
A0A812PRX4 32-295 None
A0A286I731 28-291 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.