DPCstruct | MC21295

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)119 ± 14 aa
Standard deviation of domain lengths13.77
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score90.46
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)34.45
Pfam Score90.54
Assigned Pfam label(s) CL0036- PF12972

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D3FIN0 204-317 MIVLDLFADVKPIWQMSSQFYGVPYIWCMLHNFGGNIEMYGILDSIASGPIDARTSHNSTMVGVGMCMEGIEHNPVVYELMSEMAFR…
A0A5N7CPV7 1-114 MLILDLFSKSEPQWQRTKSYFGKPWIGCQLHDFGRNMGLYGQIMNVTLSLIDALESPDSLVGFRLTMEGQEENEIIYDLLLVQAWSA…
F2UT44 545-665 None
A0A6A4VE68 346-441 None
A0A835IQU3 10-107 None
A0A7R9AWU4 157-251 None
A0A6J0PLB7 237-350 None
A0A1Y1NFQ6 378-504 None
A0A2E3MTX5 400-528 None
A0A4S4DES6 87-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.