DPCstruct | MC21282

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)143 ± 23 aa
Standard deviation of domain lengths22.70
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score73.48
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)31.16
Pfam Score93.42
Assigned Pfam label(s) PF03791- PF03790- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I1QHB1 4-121 GGEADAARCKAEILAHPLYEQLLSAHVACLRIATPVDQLPRIDAQLAQSQGVVAKYSALAAAAAGDDGRELDQFMTHYVLLLCSFKE…
A0A2K3LBP0 2-130 HNHHQGGGGGSPSSSSNEAEAIKAKIIAHPQYSSLLQAYMDCQKVGAPPDVVARMVAARQEFEARQRSSVKSRENSKDPELDQFMEA…
A0A6J1BR77 51-233 None
A0A067JLR5 10-124 None
A0A835RUI9 28-263 None
A0A0A8Y0L7 20-208 None
A0A7I4C370 217-342 None
A0A834TXQ5 47-200 None
A0A438DV37 110-263 None
A0A445D1H1 41-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.