DPCstruct | MC2127

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)99 ± 10 aa
Standard deviation of domain lengths9.87
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score73.90
Mean fraction of residues predicted as intrinsically disordered0.51
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)44.46
Pfam Score83.93
Assigned Pfam label(s) PF03247- PF01352- PF09514

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5G2R6D2 13-95 EDAQKSEKKSKAFNDISKYFSKEEWAKLGYSEKITYVYMKRNYDTMTGLGLKATPPTFMCPRKQTIESSGHDSEDQDEPPKEA
G1QTT6 1-98 MNGDNDCAKRARDDAQIPEKIQKAFDDIAKYFSKKEWKMKASEKITYVHLKRKYEVMTKLGLKVTLSPFMHNKWAADCQGNDFVKDR…
A0A7J8AVC6 1-100 None
A0A6J0Y5J4 1-96 None
Q80ZT4 1-97 None
A0A6I9JRI7 17-109 None
L8YB62 13-141 None
Q8C5Z3 38-132 None
A0A2R9B8S0 1-100 None
M0RBX4 39-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.