DPCstruct | MC21213

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)171 ± 18 aa
Standard deviation of domain lengths18.32
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.69
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)30.50
Pfam Score93.81
Assigned Pfam label(s) PF07627- PF07631

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q3JSY5 60-208 AKKLLDDPRAEQVLASFHGQLLDVSSYGKGVKSTEVYPGFTEELRPMFAQEAGLFFANVMGAERGGLRELLTSPVTYVNDKLAPIYG…
A0A150U300 1-143 MLLAGAAGSSLHQWLGLSELRKAQKDRELFPAYGEAMASAMLNESARFADHVVRQGDGLLRTLLSADYTFPEDPLFDLYELEPPDGF…
A0A2T6FJM5 415-588 None
B4D2Z2 2-188 None
B4D7Q6 323-515 None
A0A4Q6FRM4 282-457 None
A0A1P8WEV3 803-991 None
A0A349VIX0 375-507 None
A0A800JJF4 2-163 None
A0A517SX76 589-736 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.