DPCstruct | MC212

Metacluster Properties and Pfam Annotations

Number of structural domains354
Mean domain length (aa)286 ± 67 aa
Standard deviation of domain lengths67.10
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score89.54
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)18.19
Pfam Score98.92
Assigned Pfam label(s) CL0192- PF03747- CL0145- PF20118

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5F7ZZV0 2-206 RVAGISLAYSSVQDVQKFARLSAQLTHASSLGYNGAILQALAVHLALQGESSSKHFLKQLLGHMEELEGDAQSVLDARELGMEEHPY…
A0A1F4U670 23-279 LRAGQVTDDTILTQATVDSLIRRRSLDPADIALNLGRAFKKNKDLGRGFGQATITALTRILKRRPWNMVGDNNSLGNGAAMRIAPIA…
A0A7K2AVX2 20-387 None
A0A1Q9CD62 228-510 None
B0EJU1 1-188 None
A0A3N4L158 3-322 None
A0A5P2CTB4 28-334 None
A0A1G5ATA1 1-276 None
K2SJA6 2-222 None
A0A0G4HI97 63-431 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.