DPCstruct | MC21163

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)225 ± 23 aa
Standard deviation of domain lengths22.94
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score81.19
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)29.81
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y8D6S6 87-325 SEVVRAIGELRGSESFAGKKEADEILGKAIRAMGPERVLSILPLNLIKPKAGQPGRAWMLPILRDYVSNTNLQHFRTELEPLSQAML…
A0A2G2Z1G9 1-217 MLQSLVDMQKLPDEDFPYRRQLHECVGSAVGAMGPESFLALLPLKLDIEDLSKSNLWLFRILKQNIIGAHLSFFTNSIMSMVGAMKQ…
A0A0B0N7K0 302-555 None
A0A059A2S0 173-390 None
A0A835MWY4 168-417 None
A0A7J0FI01 4-230 None
A0A0M0K010 192-431 None
A0A2G3BZ66 36-290 None
A0A2U1Q546 249-422 None
A0A3P7J9W4 1-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.