DPCstruct | MC21159

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)87 ± 11 aa
Standard deviation of domain lengths10.70
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score87.59
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)23.81
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D8JWI2 29-113 ADIHEQRRERGFVCFTDHYHYGSSSGLSSKKAAQAAAIKSWADFVNFEYGGAWTSWARSGSKSIKCDHAGTGGAWSCDVNSRPCR
A0A5J4DYW3 11-101 GLMLYLLLAVQAEAAEDKTKSCKDKITAVGRPNRIQSLSSMSAVIQWTQRANELGKQYGQWHNALRTDLSCKLMQRSGYYVCYASAK…
A0A037UVF5 15-103 None
A0A6N6T2V5 144-241 None
A0A857CD04 21-107 None
A0A125NWA5 1-81 None
A0A109BLP4 73-154 None
A0A433A8W8 148-243 None
A0A4Q5RZ81 13-116 None
A0A433B8V7 3-81 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.