DPCstruct | MC2114

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)165 ± 11 aa
Standard deviation of domain lengths10.92
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score85.70
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)19.60
Pfam Score100.00
Assigned Pfam label(s) PF08847

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E5PH95 122-292 VCKSDGPAAGRTEVEHLEVASELLASCDIYPFVVRYSHHALGSGPDEIVRLRQMRGSLVISFDVPQHDPREVWEVPEVRAYVTKLAD…
A0A369QSR5 10-161 ELDPIVIVISRDEVEAGDIQPSLSALQSCIASIDMIRDRFERLDVAFHGYNDDSREVFEIPEVREFVHRLDGEFPFWLFFLSKSYLG…
A0A6B1TIL5 174-335 None
A0A5C8AUB7 2-153 None
A0A1E3C136 15-170 None
W4QMG0 2-141 None
G2DW53 31-208 None
A0A4Y7IYF5 199-374 None
A0A443PJY0 132-285 None
A0A7V7MQF8 142-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.