DPCstruct | MC21126

Metacluster Properties and Pfam Annotations

Number of structural domains185
Mean domain length (aa)256 ± 69 aa
Standard deviation of domain lengths68.52
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score86.48
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.74
Pfam Score99.07
Assigned Pfam label(s) CL0240- CL0533- PF04387

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q0RR53 1-206 MNAAVRSAVRVGITEGHKMFAVNDGFEGFYKGQIKEIKWGDVGGWTGQGGSLLGTKRTLPGKHLDKIAEQMRIHNINALLVIGGFEA…
A0A641VQU5 4-241 VKCIGILTSGGDAPGMNAAIRAVTRAAIYNGLQVKGIYRGYKGLVTGEIKEFKSQNVSNIIQLGGTILKTARCKEFTTPEGRQLAYD…
A0A351I961 121-417 None
A0A287QJ91 11-264 None
A0A287QPG2 52-231 None
A0A2R6QFI5 3-190 None
R5WGJ8 2-300 None
A0A4S4DCQ2 326-470 None
A0A3Q0JCM1 235-376 None
A0A843WXV4 89-251 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.