DPCstruct | MC21121

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)83 ± 13 aa
Standard deviation of domain lengths13.47
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.50
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)44.51
Pfam Score76.67
Assigned Pfam label(s) CL0179- PF09360- PF10660

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5N5SKX3 3-71 KGGHCNLSVKKNESKVVDSIDMEDLGDKASFCRCWRSAKFPYCDGTHGKHNTTTGDNVGPLVIKKKELS
A0A452FWQ2 31-113 VGYLAYKRFYVKDHRNKSMVNPHIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPLCDGSHTKHNEETGDNVGPLIIKKKDT
A0A183BDJ6 19-102 None
A0A4W5L680 125-211 None
A0A7S3C085 7-79 None
A0A5F4W0P6 53-127 None
A0A673W7U9 29-123 None
A0A7S4P8M5 35-114 None
A0A498N8E5 141-221 None
A0A2K1IJA8 197-283 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.