DPCstruct | MC2105

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)92 ± 9 aa
Standard deviation of domain lengths9.38
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score86.47
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.06
Pfam Score77.78
Assigned Pfam label(s) CL0369- CL0263

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W5KQ98 20-110 EELPRCALCGRRIPSFARQSEHHLVPKSRGGTFGPTVLLHQICHNVIHALFSEKELAWRLSDIEALRAEPEVATFIAWVRSKPDDFH…
F5LJP6 6-96 EQGTCELCGRHEVKRTEHHLTPKEKGGTFLPTAMLCIPCHKQIHALFTNEQLERDLHTLDALRGDERMRAFLKWIRKQPSASLPRVR…
A0A4Z0YZ41 196-289 None
G3JCV2 86-168 None
A0A7S2XRD7 140-251 None
A0A1B7Y5G4 341-422 None
A0A812UCS3 298-401 None
M2SB47 1-74 None
E3QLL5 10-100 None
A0A6S7BEU1 12-108 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.