DPCstruct | MC21017

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)134 ± 17 aa
Standard deviation of domain lengths16.52
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score80.08
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)43.15
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S4A0H7 91-222 GDSSSDLLKQIEKKESVAYVEKRAVMRDWLKALFRGQAYATIGLSFLLSYDLIPFVDLDLSIRVLGFWSWWLFTVPSLRSIKPLPAP…
A0A7C8ZAL9 60-193 VVNKTAATFAPRASTARKNPAIPGTALYTIFEVQGYASMLMGGVLSFNLLFPSTEPDIWRLMGMWSIWMFTIPSLRARDCSNNEKEA…
A0A7S4P370 184-325 None
T1M2Q9 9-152 None
A0A2N9GVG3 586-748 None
W7TZ94 118-261 None
A0A061S3G0 95-220 None
A0A1Y5IL61 6-130 None
R1EB73 51-174 None
A0A0G4GG26 153-281 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.