DPCstruct | MC21015

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)130 ± 18 aa
Standard deviation of domain lengths17.88
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score89.85
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)33.34
Pfam Score100.00
Assigned Pfam label(s) CL0344

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A661KTG8 12-132 GKAEEPNLLQKILSMTVQERKDFWDKQFMKCIKCYGCIDVCPVKREEPEELSLSKWIEKAKVPPPYPAFHLLRAYQVWDTCILCGEC…
A0A7C2DZJ2 35-160 SREVIEKLESLPEKERLEWWKGQFRRCVKCYGCRNICPMCFCKDCALEDPHLVEPGVIPPEFPAFHVIRALDMAGRCIDCGLCEEAC…
A0A1I4QWQ6 101-208 None
A0A7R9RDC2 81-240 None
A0A7V0XEC3 184-312 None
A0A2N3G544 125-218 None
A0A7Z9ZG54 291-448 None
A0A7C1BMI4 23-162 None
A0A847EHE4 43-181 None
A0A1V5DZH6 20-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.