DPCstruct | MC21011

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)181 ± 28 aa
Standard deviation of domain lengths28.22
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score69.22
Mean fraction of residues predicted as intrinsically disordered0.71
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)28.68
Pfam Score100.00
Assigned Pfam label(s) CL0225

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I5DFX6 2-135 MSLLVLGIVVIAPNLKAYIEQRQQIAQLEASVAESEDEIERLSVERERWNDSTYVMTQARDRLFYVNPGEVSFIVLNDVDSALLGKD…
A0A0Q7PVL1 1-187 MAERRPNRGSGPRGTRRPTSPRGSRPRPGAVATPGTSPRRPAARRTPVRPKLTGRGTVLVLVLAVLTVSFASSMRAYLEQQSHISDL…
A0A1R4I7S9 1-175 None
A0A0Q6FKW2 2-138 None
A0A328LH75 37-241 None
A0A1D9ML48 19-210 None
A0A5M9ZTF5 5-194 None
A0A542Y596 16-144 None
A0A6I3J1D7 2-187 None
A0A421AXA0 2-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.