DPCstruct | MC20967

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)339 ± 54 aa
Standard deviation of domain lengths53.81
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score70.85
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)19.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U6JWK5 1-300 MADITHRSRRESARTRTKKKKKKGGEDDRFGLMKEQHTKQEKKKKKKKKKEKKEKKIHLLQTQGQPALLIVSVPLPYPEGQEEQQEQ…
U6H1Z2 3-314 EDEVSIVEGCLELEEEMGVLGERAISISEGDSSGRVAELEAMLSAAAKESVMQGGLGTDLQVQEQEPEEQESDMPVGDTRDPPNTEQ…
U6JUW3 1-433 None
U6KIU1 2-235 None
U6KCD8 7-365 None
U6K4W1 186-463 None
U6K3X5 120-493 None
U6JWF8 1-268 None
U6JTW8 1-341 None
U6GUI2 1-427 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.