DPCstruct | MC20892

Metacluster Properties and Pfam Annotations

Number of structural domains136
Mean domain length (aa)266 ± 38 aa
Standard deviation of domain lengths37.50
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.67
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)23.27
Pfam Score95.92
Assigned Pfam label(s) CL0168- CL0672- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3HP96 126-400 FTNLGATGRLGPTSVGKYYDGQDHQGKVTLVNGTQFFTIPVSGLYRIRAAGAAGGCDNGRCHDRSHGAVVAGTFNLKAGRQLKILVG…
A2EY31 33-256 CSSSIQTCTPYVVSLSRGTYQLELFGASGGFPNNDPKLGGHGSYTKGNLVVDHDMKLYVYLGQQGKLNGPRTFNGGGRGSANAGSGG…
T1PHZ5 164-474 None
A0A518VAL6 13-287 None
A2DIP6 8-224 None
A2DRN8 20-282 None
A2DX38 22-277 None
A2F5G1 32-255 None
A2FID4 4-248 None
A2FD39 11-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.