DPCstruct | MC20890

Metacluster Properties and Pfam Annotations

Number of structural domains51
Mean domain length (aa)421 ± 93 aa
Standard deviation of domain lengths93.03
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.22
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)22.28
Pfam Score100.00
Assigned Pfam label(s) PF12166

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P9HKR3 24-365 KCVFQVVLVFGIHFWMFFILPGVTERRFNRNPIAQLWYFVKCIYFGLSAYQIKCGYPNRILGNFLTKNYNYLNLFLFQGFRMVPFLT…
A2EK50 27-401 AISFFYCQNDISYMPGSLIFYLIVRLISHFCYSFHVRYGKTVLDFVYPDFKRDVHAIFSKNMSLKRIPLIFEIKSLFHWMSQDTYVK…
A0A821IUN5 72-405 None
A0A653DHE2 769-1246 None
A0A044T179 1088-1537 None
A0A0R3QQZ3 92-474 None
E7FD74 1898-2428 None
A0A7S4PQ97 2-423 None
A0A067RJC4 315-759 None
A0A7F8K7I5 214-587 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.