DPCstruct | MC20867

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)350 ± 93 aa
Standard deviation of domain lengths92.90
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score80.74
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)21.30
Pfam Score100.00
Assigned Pfam label(s) CL0323

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A093UTL7 142-427 EVSRGNLKGLLETCSQDLSGAQLQGFLQSAMMCLAKTHSYTYNFVRATRTQSIPANLGDSVGDFYQKCIEVELPDLDAARFIASALI…
A0A7U2R165 192-537 YNELLDALHLRSVELGECFSVVRLFRLAGDYLSPLARYQRLRDEVYRQREEVANTKNGHQMLFSAVHLMSFFEKAVQHTARTISQEF…
A0A194VMA6 94-422 None
A0A2U3DRS0 189-468 None
A0A2U3DPT9 76-368 None
A0A401L9R2 2-236 None
X0H1J6 3-312 None
A0A6A5TKZ4 109-435 None
A0A1Y2DD17 25-249 None
A0A162MFL5 99-443 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.