DPCstruct | MC20835

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)148 ± 27 aa
Standard deviation of domain lengths26.98
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.29
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)41.33
Pfam Score100.00
Assigned Pfam label(s) PF05731

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P7L4B1 98-238 SAEADLLKENLIILVSGTIVPSLSFKNKAIRKTAMEMLDELSKSDPEFVLKVVNNIAQELNIRFTTNFLLAYAAANEACRPYIGKYF…
A0A452H9Y5 48-207 QRSGRHGWLWPGGKAASPAALSELCEELAQLEPEFILKVSLYTRQELNIRGTANFLLALAARLPPCRPHLRRYLCATLQLPSDWIQV…
L8GW11 8-195 None
A0A3Q0E335 214-409 None
A0A6A5DET8 41-181 None
A0A2G8LIZ8 58-197 None
A0A3R7LM57 54-240 None
A0A670ZI67 37-181 None
A0A5C6P162 208-356 None
S4RXY6 2-148 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.