DPCstruct | MC20808

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)151 ± 23 aa
Standard deviation of domain lengths22.86
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score89.01
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.05
Pfam Score100.00
Assigned Pfam label(s) CL0377

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A853FVM8 1-154 MLSDDLIHALARDFYEAEQSRVQVRAPSVRYPDLTMADAYAIQNAWVEMKIASGNPIKGFKIGLTSRAMQMAVGISEPDHGVLLEDM…
W7WPR2 1-147 MPPAAHDAAQLLWRCRQSGNVIDALPDALRPGDAAAGHAIQAALAQVAGSPVVGWKIAATSAAGQAHIQVDGPLPGRILGSFVHAMG…
A0A1I3G9W0 3-161 None
A0A7S1XQ77 24-216 None
A0A3S5J9R2 18-154 None
Q5BHA0 63-229 None
A0A535VRH6 5-147 None
A0A3E0CVM8 25-168 None
A0A354VHL5 8-168 None
A0A7S0TUR2 65-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.