DPCstruct | MC20789

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)103 ± 10 aa
Standard deviation of domain lengths10.04
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score81.97
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)28.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A558RDH6 28-115 FEAVLDRLLGEQVRADGACGVDLWCALTNTRWFGPDGVEVSYGFRRAGHAVAWVREEGDDLTWYCSGEPGQVAQWIEEVLAGAGWSWR
A0A519CSY0 1-106 MLNECNLERDLIDCQPIKDKVRKDDRYATRLYDALCNTKWYHDSDVHGGRTKGDAWSCSWRYAGDLVAKLRVSHEDYLDYYCSGNEG…
A0A2R4MEK1 5-97 None
A0A5R9P146 2-99 None
A0A4Y3ZQL4 1-93 None
A0A0G4I990 12-112 None
K5Z1T7 44-160 None
A0A7U0G486 88-203 None
A0A4R2T2Y5 85-196 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.