DPCstruct | MC20763

Metacluster Properties and Pfam Annotations

Number of structural domains308
Mean domain length (aa)234 ± 53 aa
Standard deviation of domain lengths53.05
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score88.43
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.76
Pfam Score98.65
Assigned Pfam label(s) CL0027- CL0033- PF01063- CL0240- PF19275

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D4F6T9 7-138 GITLTVSPIRLARQPLLAGIKHLNRLEQVLIRAHLAQTQADEALVLDTQDRLVECCAANLFWRCGQQVFTPRLTQCGVDGVMRQRIC…
A0A3B1IPT5 3-280 ANLFEGMKAYRGADGRVRLFRPMLNMTRMLKSANRACLPGFDRGELLECIRKLVEVDQEWVPQSESASLYIRPTFIGTEPSLGVKKP…
A0A7G2M474 19-200 None
A0A496BQ25 18-204 None
A0A0D9VEI6 32-254 None
A0A318SC69 18-225 None
B5VQ57 6-202 None
A0A812PF49 11-268 None
A0A2W6AJZ5 2-152 None
A0A7V2UKE9 273-459 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.