DPCstruct | MC20747

Metacluster Properties and Pfam Annotations

Number of structural domains211
Mean domain length (aa)113 ± 21 aa
Standard deviation of domain lengths20.66
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score71.92
Mean fraction of residues predicted as intrinsically disordered0.50
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)35.27
Pfam Score96.81
Assigned Pfam label(s) CL0274- PF10533- PF03208

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4MXP1 5-82 KVSVRARSEAPMTTDGCQWRKYGQKMAKGNPCPRAYYRCTMATGCTVRKQVQRCAEDKTILITTYEGNHNHPLPPAAM
A0A103XJ01 8-122 VNNLNKRKFVECEEGNTSGRTETLHQGSLKRPNEGVTRVVKDGYQWRKYGQKVTRDNPSPRAYYKCSFAPSCTVKKKVQKSVDDAHL…
A0A5N5J8L2 442-523 None
A0A803PYN4 119-204 None
A0A445CUL7 32-145 None
E7CEY0 27-157 None
A0A396HTL3 63-184 None
M4DRI0 21-143 None
A0A834T8R6 347-462 None
A0A3S3Q860 80-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.