DPCstruct | MC20736

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)214 ± 34 aa
Standard deviation of domain lengths34.37
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.83
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)33.13
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U2EHC1 226-431 LNCRKESEMYNPEIFCRILRPKNYPIARFPDNPEFSLALMQQVAVNLSIGFDNEQIRSVNGPPGTGKTTLLKDIFAELIVEQAYEMA…
A0A553ANC9 67-256 LNSFFIPDLERAMASVSAGETPAALRQYLTPLPPQDRCNLFSAQGRETIVDMLAPDRMNRGRWFADPRHAMSLMQQFAINAATTRLA…
A0A2S0JAV3 59-289 None
H8K2W5 1-208 None
U2CXI4 191-395 None
A0A446C8P6 35-303 None
A0A7X7KU51 197-392 None
A0A529M875 331-549 None
A0A6B3VWZ0 2-297 None
A0A227KGB6 276-506 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.