DPCstruct | MC20726

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)82 ± 10 aa
Standard deviation of domain lengths10.34
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.36
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)35.23
Pfam Score97.22
Assigned Pfam label(s) CL0167- PF19769- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A177EYK8 100-169 EPTNHNHKNPRLPQRTPATAFDCHFCNARKAVKVKVDEKAGRGSLKCKNCHIKFACAVDNLSAAVDVHAA
A0A7M7RGD1 1-79 MGRRRAKKKPPQKKKMLGTLETQFTCPFCNHEKSCDVKMDRTRNVGVISCRVCLEDFQTSITYLSEPVDVYSDWIDACE
F2RNK9 81-166 None
A0A3N7HI58 39-123 None
A0A7C2ZBD4 2-63 None
A0A0G4HF22 1-86 None
A0A1Q9CL99 921-1009 None
A0A6G1IPT1 130-220 None
A0A3Q7QYT5 1-63 None
A0A835XNX1 1-90 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.