DPCstruct | MC20676

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)179 ± 28 aa
Standard deviation of domain lengths28.09
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score70.69
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)35.83
Pfam Score87.19
Assigned Pfam label(s) CL0081- PF14048- PF02008

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R7UD31 2-156 RHDANLVLPIRQTASIFKQPVTVIRNRPESITRSDLKHGPQEQPKQLFWEKRLEGLHACDTNEERFKSLDLPHNIQGAGPNLSTENL…
A0A7I0Z153 37-212 TMLLCKVKKQARAQYEYNRGFRSDASLVPPIRQTASIFKQPVTVYKTQESKVKTDLKQGTQEKPKQLFWEKRLEGLTACDANGVIGT…
A0A194RD56 44-234 None
A0A3Q1EG39 2-180 None
A0A2A2KFQ8 1-157 None
A0A0V1ACN0 22-201 None
A0A6P6CI33 1-177 None
G1T1U1 37-204 None
A0A6F9CTB6 280-408 None
A0A7R8X1H1 565-786 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.