DPCstruct | MC20665

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)134 ± 18 aa
Standard deviation of domain lengths17.70
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.21
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)25.81
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H8IY76 1-119 MDKYERRRLNLIKLRDEKCNGVNAEIARKIGKDQSYVNRIFYPEGKKGKKRIGDDIKEIIETEFGLPTGWLDGVDSNNILGIDETKL…
A0A1G6JAP4 1-159 MDNKTIRYTNVRYLVDLIGGVSNFAQRLDKGQSQTSQFAGTNPIKGIGNKIAREIEDAFSKPHGWLDVAHPELWGVQSNIEQDTSSR…
A0A4P8IPI4 26-164 None
A0A2X3KFB8 2-106 None
I4KXA8 1-153 None
A0A349H407 1-124 None
A0A1I4C4J6 21-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.