DPCstruct | MC20644

Metacluster Properties and Pfam Annotations

Number of structural domains1193
Mean domain length (aa)182 ± 39 aa
Standard deviation of domain lengths38.59
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.03
Pfam Score99.32
Assigned Pfam label(s) CL0125- CL0220- CL0356- PF00183- PF19437

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A495EWX4 375-532 None
A0A1X7V6J9 1089-1245 None
A0A1X7V559 129-343 None
A0A1X7V0H2 175-358 None
A0A7J6M6B7 841-989 None
A0A4S4KHN2 48-220 None
A0A820N4E1 209-384 None
A0A1Y2B645 39-226 None
A0A0C4DY86 1014-1182 None
A0A815A241 232-448 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.