DPCstruct | MC20644

Metacluster Properties and Pfam Annotations

Number of structural domains1193
Mean domain length (aa)182 ± 39 aa
Standard deviation of domain lengths38.59
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.03
Pfam Score99.32
Assigned Pfam label(s) CL0125- CL0220- CL0356- PF00183- PF19437

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183IKG9 28-280 None
A0A2P4PV96 3-291 None
A0A1D1ZWZ6 33-183 None
A0A7S4EBY6 40-308 None
A0A6S8NJB3 204-382 None
A0A4D8ZER5 408-565 None
A0A2P6V4F0 828-1000 None
A0A168RZQ7 400-557 None
A0A168R6X6 88-217 None
A0A5B0SJN1 1-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.