DPCstruct | MC20644

Metacluster Properties and Pfam Annotations

Number of structural domains1193
Mean domain length (aa)182 ± 39 aa
Standard deviation of domain lengths38.59
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.03
Pfam Score99.32
Assigned Pfam label(s) CL0125- CL0220- CL0356- PF00183- PF19437

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821P0I3 172-353 None
A0A2P5YC70 321-449 None
K2ESG0 515-657 None
A0A5C3EGQ8 510-667 None
A0A5C3ECK5 763-912 None
A0A2V1BX27 179-378 None
A0A1R2C8L6 157-314 None
A0A2V0P845 8-167 None
A0A2V0NY19 3-149 None
A0A6S7J3W3 2-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.