DPCstruct | MC20644

Metacluster Properties and Pfam Annotations

Number of structural domains1193
Mean domain length (aa)182 ± 39 aa
Standard deviation of domain lengths38.59
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.03
Pfam Score99.32
Assigned Pfam label(s) CL0125- CL0220- CL0356- PF00183- PF19437

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A9M1I5 70-289 None
A0A2V1BJ45 95-277 None
A0A4Y9Y1K1 220-421 None
J3NK67 101-269 None
A0A821UT78 49-213 None
A0A821T6S1 1-167 None
A0A821SGK2 62-220 None
D8LPN8 13-197 None
D8LLK1 475-612 None
R4XDX5 33-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.