DPCstruct | MC20644

Metacluster Properties and Pfam Annotations

Number of structural domains1193
Mean domain length (aa)182 ± 39 aa
Standard deviation of domain lengths38.59
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.03
Pfam Score99.32
Assigned Pfam label(s) CL0125- CL0220- CL0356- PF00183- PF19437

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A150FXL4 23-165 VVRREIPADNSCLFNSIGYVMHKSKTRAPHLRNVVARQVAGDRTTYSDAFLGMSNEAYCSWIRQPFNWGGGIELSILAQAYSMEIAA…
A0A1S4DUT3 46-200 PSVDEAASDHERLLDRLQVYDFVERKVQGDGNCQFRALSDQLYGTPDNHELVRQKVVNQLMAHPEIYEGYVPMAYDEYLEKMSRNGE…
A0A7E4WEA0 395-539 None
W5M3T7 48-297 None
A0A7E4W0Y1 641-802 None
A0A7E4VQZ5 1021-1175 None
A0A6S7NFQ7 134-326 None
W5MR22 16-152 None
A0A821QUE2 179-347 None
A0A7S1V4T9 1-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.