DPCstruct | MC20590

Metacluster Properties and Pfam Annotations

Number of structural domains803
Mean domain length (aa)257 ± 55 aa
Standard deviation of domain lengths54.55
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.81
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)14.65
Pfam Score97.99
Assigned Pfam label(s) PF04227- PF11807- CL0063- CL0118- CL0015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8E4R1 15-172 VAAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAKTSIVCKVGKDSFGNDYIENLKQNDISTEFTCQ…
A0A7V1EAC1 6-281 NHIVVIASFMMDLTTKLKKIPVRGETVFGEEFKIGPGGKGSNQAVCAKRLGLNITVVAKLGNDVFGREALNNFKKEGFETDFIFIDH…
A0A3D3EHA6 7-268 None
A0A1Y2SLN0 2-181 None
V4Y6W9 2-180 None
A0A6A6L612 7-184 None
A0A7C5U5G9 8-225 None
A0A2R6CZN1 8-258 None
A0A0D2NY90 12-241 None
K2SLP9 285-583 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.