DPCstruct | MC20577

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)98 ± 11 aa
Standard deviation of domain lengths11.18
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.26
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)40.28
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452ZJ09 135-220 VPPVDVDKVRCIIRNIVRDWAQEGQIERDECYKPILEELNRLFPDRSRPPSCLVPGAGLGRLALEISSLGFVSQGNEFSYYMMICS
A0A6M2EVS0 4-105 HLGEHLVRCIIRNIVRDWAAEGMMRHCFPVSNSQKERDQCYKPILEELNSLFPSRCNKSPPTCLVPGAGLGRLVLEISCLGFVSQGN…
A0A2H9TPY0 122-219 None
U6LHQ2 234-314 None
A0A0V0ZVI3 87-199 None
R1GHB2 67-164 None
A0A834T2E8 377-463 None
A0A2P2MED6 272-364 None
A0A284QP30 110-214 None
A0A0G4HL64 256-369 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.