DPCstruct | MC20574

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)148 ± 23 aa
Standard deviation of domain lengths23.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.16
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)21.40
Pfam Score100.00
Assigned Pfam label(s) CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D9LLC7 1-96 MSWYTPQELVGLPGLPGTEQNVRAFAKRHGWQGHRRLGSKAIEYPAAALPLETQVALMDLKSRAALAASAQALNDLADHHQALAEQL…
E8KH41 1-127 MKEWFLAKELVGIGGLPNHATNVTRQAKKQNWEARAAKGVKGGGLEYHISSLSLETQRALRLQAALAEVKPPEMAQPKLNLDLVRKF…
C6SM66 1-173 None
A0A2X3JF63 3-137 None
A0A7V2EYC7 136-282 None
A0A0P4UWQ3 92-258 None
A0A840NVX7 1-136 None
A0A837Q7U6 2-147 None
A0A6S5WTF4 14-163 None
A0A1G1FYI3 1-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.