DPCstruct | MC20558

Metacluster Properties and Pfam Annotations

Number of structural domains117
Mean domain length (aa)59 ± 9 aa
Standard deviation of domain lengths8.78
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score75.92
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.28
Pfam Score96.46
Assigned Pfam label(s) PF00082- PF00187- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2A783 713-770 None
A0A1Y1ZYE0 200-241 None
D8TGS0 2-59 None
A0A1Y1YQ90 230-290 None
A0A1Y1XQP1 125-190 None
A0A1Y2FRK3 326-395 None
A0A1Y2FR59 6-63 None
A0A1Y2FMQ6 70-151 None
A0A1Y2EVL4 9-62 None
A0A1Y2ES57 508-559 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.