DPCstruct | MC20558

Metacluster Properties and Pfam Annotations

Number of structural domains117
Mean domain length (aa)59 ± 9 aa
Standard deviation of domain lengths8.78
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score75.92
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.28
Pfam Score96.46
Assigned Pfam label(s) PF00082- PF00187- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X0HV15 79-131 AAPPAKLTITPDSTCGVRTGFKCAEGSCCGASGWCGSTPAHCGTGCHFAYGKC
A0A1Y1UW30 27-83 KSSTSTTKLPISTNSSGKCGKGYGRCSSGYCCSKYGYCGKTSEYCGNGCQSEFGKCN
A0A1Y1XGH7 98-163 None
A0A1Y1XHG3 112-173 None
A0A1Y1XJF4 933-990 None
A0A074W4W7 33-104 None
A0A835YTT5 304-353 None
A0A178DKG7 62-131 None
A0A383VMG1 556-618 None
A0A1Y1XDB5 278-321 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.