DPCstruct | MC20527

Metacluster Properties and Pfam Annotations

Number of structural domains344
Mean domain length (aa)173 ± 35 aa
Standard deviation of domain lengths34.83
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score81.63
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.42
Pfam Score84.98
Assigned Pfam label(s) PF20381- PF04011- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V0YUY6 2-124 KWFEDRLSGFYQKYGGEIVIVTLKSTKPIKPSEYVFWLFNRWDIGGEKNAGIMILLALSERRIESEVGYSYEHIISDVESGQVLDDY…
A0A2W1JKF9 20-206 IASSTLPAIAVSIEQVPNPRQNNGGWVTDMADVLSAPTELKLNQMISELEAENSSEIAVVTVPETSPSKSPKTFATELFNTWGIGKK…
A0A354NFZ3 21-159 None
R5VV64 29-232 None
A0A3D3NPP8 32-192 None
A0A2R3MX68 38-170 None
A0A323V5A3 27-173 None
R6QM81 72-314 None
A0A2Z5TF40 1-112 None
A0A3E1EG62 31-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.