DPCstruct | MC20518

Metacluster Properties and Pfam Annotations

Number of structural domains131
Mean domain length (aa)250 ± 59 aa
Standard deviation of domain lengths59.07
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score78.20
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)21.08
Pfam Score69.37
Assigned Pfam label(s) CL0125- CL0416- PF16178- PF06025- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C0NZ68 17-221 VDYVVLYRFSSIDKNEAKEQFKKLIRALSDVGLQTEVRPGIDQSLLIFVKAQEKYLGKALYRSRVRDWLHGVRNSQPDPDAKGSCIP…
A0A7R9QZC1 15-270 IDFVLVFRTKDVKLSEDMSKSRQIYEQNLIEEGLILEYTDSIGSGEYTYVHIFAPWDLLTRYAEVMKLRMPMKTIQSNMKVLFDEEY…
A0A1A7XS53 30-280 None
A0A6I9YYE0 25-279 None
A0A067BRW1 34-288 None
A0A672PXH2 15-290 None
A0A0D8XGL6 24-265 None
A0A183MKS1 36-282 None
W4GQA4 23-228 None
A0A2A2K345 8-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.