DPCstruct | MC20499

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)380 ± 37 aa
Standard deviation of domain lengths37.20
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score81.86
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)15.92
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M3I3T9 2-361 LFEQGLADPRGLEYRSIVVRVGSVWGSSHTIQTRGWVIDSFYAIGWNGLVYPVISIGEKQNLQSDILSIVSKDKKERAEYEKKYSGK…
A0A7V8J038 1-449 MAFLLIAFPLAADPAADLERILRSLDADDADLRDRAQAELGSWCEATGAEAEAMLKKTRDGVSPEVRARIEEQLGVFERGREVRKEV…
B4D3W3 58-426 None
A0A5B9W5V5 54-447 None
A0A4Q3V8J6 14-355 None
A0A517PI80 1-428 None
A0A5C1AR58 1-391 None
A0A2E0QYZ9 16-396 None
A0A7W1VUU9 25-383 None
A0A068NUX4 9-339 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.