DPCstruct | MC20491

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)200 ± 37 aa
Standard deviation of domain lengths37.44
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.21
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.69
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2SUN2 6-185 LWPKLGDMGVDTSLFGQCLTRFGILAGSECVKIDEEVISLISSVLSKEFDAVSDVPKQYRWTKKPSPSSHSAYITTAHSKLDDFVSE…
A0A7R9SZ17 25-225 AVRAMAPLGDAAAVAIRSALHDIADDRMEKIAVRIRELLVTPLATKCCGMLKQLRGITATYRMTNKPAPERASHYVPSVLAPLRTFV…
A0A5B6W2R2 23-223 None
A0A7S3C6T2 87-297 None
A0A7R9ZL98 11-166 None
A0A2A2KME3 406-600 None
A0A146I9S7 612-841 None
E3K8M4 83-249 None
A0A5N4DJZ7 111-352 None
F8NV43 569-790 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.