DPCstruct | MC20467

Metacluster Properties and Pfam Annotations

Number of structural domains104
Mean domain length (aa)117 ± 25 aa
Standard deviation of domain lengths25.49
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score85.12
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)24.65
Pfam Score85.74
Assigned Pfam label(s) PF19278- PF02538- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W0WB80 1-63 PVFFAEAGDYVDCPIYDRYALPAGATLAGPAVVEEFDSTTVVHPGFSLGVDDVGNLTIEKEDS
A0A836X4L9 49-136 DRVGNGIRPTYKGSLFLGHADEALTGSCSMFLPDISEQLDTPVYDSEKMKPGAWFQGPGIIEVRDTTIYVPREATVERDGYLNFILKL
A0A146IMS9 185-304 None
A0A6J3CF78 20-138 None
A0A432QU89 142-258 None
A0A7G2M0S1 289-409 None
K2S7Q5 133-258 None
H0EM88 484-627 None
E7F6Z6 619-737 None
A0A317WHJ4 492-624 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.