DPCstruct | MC20421

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)291 ± 21 aa
Standard deviation of domain lengths20.70
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score92.61
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)40.24
Pfam Score100.00
Assigned Pfam label(s) CL0714

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378UWG3 32-330 GLLAYRTYTASMPMPDTVVTESGQVVFTGDEITRGQELFQSRGLQEYGSIVGHGAYLGPDYTADYLRRATEDVATQLRDGGMADTHD…
A0A0W0WVL5 36-340 AWGTHKTYQLAPPLPDQFITSDGIIVMTEADIFAGKAGFQRADLMDYGSLYGMGSYFGEDYTAKYLVRLGRLVEDNMSQQQFSKPFT…
W4UKN6 35-336 None
X8C4D7 22-321 None
A0A368A967 1-250 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.